中国全科医学2018,Vol.21Issue(18):2173-2178,6.DOI:10.3969/j.issn.1007-9572.2018.00.241
急性基底动脉闭塞患者血管内支架机械取栓治疗的临床效果研究
Clinical Efficacy of Endovascular Mechanical Thrombectomy with Retrievable Stents for Acute Basilar Artery Occlusion
摘要
Abstract
Objective To investigate the clinical efficacy and safety of endovascular mechanical thrombectomy(EMT) with Solitaire AB stent in patients with acute basilar artery occlusion(ABAO),and to analyze the factors that affect the clinical prognosis.Methods In this retrospective study,we enrolled 16 consecutive cases of ABAO from Department of Neurology,the Second Hospital of Hebei Medical University from March 2015 to December 2017.All of them underwent EMT with the Solitaire AB stent.The recanalization rate and complications of EMT were analyzed.The clinical prognosis within 90 days after EMT was evaluated and its associated factors were analyzed.Results 14 out of 16 patients were successfully treated with EMT.Modified Treatment in Cerebral Ischemia Scale(mTICI) 3 or 2b level was successful achieved in 11 cases(11/16).There was no symptomatic intracranial hemorrhage,whereas 1 case(1/16) of failed endoscopic stent retrieval occurred,and 1 case(1/16) of iatrogenic dissection.The follow-up within 90 days after EMT showed that 5 cases(5/16) died.The Modified Rankin Scale (mRS) score of the survivals was(2.0±1.4).Seven cases(7/16) with mRS score ≤ 2 were found with favorable prognosis,but other 9 cases(9/16)(including 4 with mRS score > 2 and 5 deaths) with poor prognosis.Sex,preprocedural NIHSS score,preprocedural pc-ASPECTS,being comatose or hemiplegia in consultation,duration between the onset of stroke symptoms and admission time,duration between the onset of stroke symptoms and recanalization time differed significantly between patients with good prognosis and those with poor prognosis(P<0.05).Conclusion EMT with Solitaire AB stent could achieve a high recanalization rate and improve the clinical prognosis in ABAO patients.关键词
椎底动脉供血不足/支架/血管内操作/机械溶栓Key words
Vertebrobasilar insufficiency/Stents/Endovascular procedures/Mechanical thrombolysis分类
医药卫生引用本文复制引用
于江华,赵博,朱梦楚,冯晓红,史志勤,苏旭东,李鑫,陈瑞卿,赵立明,尹阔场,刘增品,檀国军..急性基底动脉闭塞患者血管内支架机械取栓治疗的临床效果研究[J].中国全科医学,2018,21(18):2173-2178,6.基金项目
河北省医学适用技术跟踪项目(GL201618) (GL201618)