中国比较医学杂志2018，Vol.28Issue(6)：121-126,6.DOI:10.3969/j.issn.1671-7856.2018.06.022
HIV潜伏库治疗策略研究
Research on the strategy of eradication of HIV latent reservoirs
摘要
Abstract
HIV latent reservoirs are the latent cells and tissues of HIV under the pressure of immune responses and antiviral therapy. Although HIV infection is effectively controlled by the advent of highly active antiretroviral therapy (HAART) and the viral load in the plasma is suppressed to a low level which are undetectable by most clinical measures, HAART is not able to completely eradicate the virus in the reservoirs. The viral rebound occurs when antiviral therapy is ceased. Therefore, the eradication of HIV reservoirs is a major challenge for the therapy of AIDS. In this paper, we will focus on the strategies of eradication of AIDS latent reservoirs.关键词
人类免疫缺陷病毒/潜伏库/治疗策略Key words
HIV/latent reservoir/therapeutic strategy分类
医药卫生引用本文复制引用
童玲,薛婧,魏强..HIV潜伏库治疗策略研究[J].中国比较医学杂志,2018,28(6):121-126,6.基金项目
中国医学科学院医学与健康科技创新工程重大协同创新项目(2017-I2M-1-014) （2017-I2M-1-014）
十三五科技部传染病重大专项(2017ZX10304402). （2017ZX10304402）
