中国药科大学学报2018，Vol.49Issue(3)：263-271,9.DOI:10.11665/j.issn.1000-5048.20180302
治疗肝纤维化药物递送系统研究进展
Advances in drug delivery systems for the treatment of liver fibrosis
摘要
Abstract
Liver fibrosis is a major disease that affects human health. Currently,drugs used for the treatment of hepatic fibrosis have such problems as low drug solubility,lack of liver specificity and possible occurrence of side-effects. In order to improve the anti-fibrosis therapeutic efficacy,various nano-drug delivery systems and targeting strategies are explored in liver fibrosis therapy. This review summarizes the drug delivery systems and targeting strategies that have been applied to liver fibrosis therapy in recent years from the types of carriers and modified ligands,which serve as a basis of designing safe and effective drug delivery systems for liver fibrosis therapy.关键词
肝纤维化/抗纤维化/纳米药物递送系统/靶向策略Key words
liver fibrosis/anti-fibrosis/nano-drug delivery systems/targeting strategies分类
医药卫生引用本文复制引用
范倩倩,邢磊,乔建斌,张程璐,姜虎林..治疗肝纤维化药物递送系统研究进展[J].中国药科大学学报,2018,49(3):263-271,9.基金项目
国家自然科学基金资助项目(No.81773667,No.81573369)This study was supported by the National Natural Science Foundation of China （No.81773667,No.81573369）
