中国药房2018，Vol.29Issue(3)：293-297,5.DOI:10.6039/j.issn.1001-0408.2018.03.02
专项处方点评模式对我院清洁手术围术期抗菌药物预防使用的干预效果评价
Evaluation of Interventional Effects of Special Prescription Comment Model on Prophylactic Application of Antibiotics during Perioperative Period of Clean Operation in Our Hospital
摘要
Abstract
OBJECTIVE: To evaluate the effects of special prescription comment model intervention on prophylactic application of antibiotics during perioperative period of clean operation in our hospital. METHODS: By founding specialist group and prescription comment group, formulating unified form for evaluating prophylactic application of antibiotics during perioperative period of clean operation, establishing comment criteria referring to Guidelines for Clinical Antibiotics Use (2015 edition), Notice on Further Strengthening the Management of Clinical Antibiotics Use, drug package inserts and so on; havivg the aid of administrative intervention and quality assessment, The special prescription comment model was established. Based on stratified sampling (according to the clinical departments, kind of procedure), Each 180 medical records were collected from our hospital during Jan. -Jun. 2015 (before intervention) and Jan. -Jun. 2016 (after intervention). The unified form for perioperative period of clean operation was formulated to comment each medical record in respects of prophylactic utilization rate of antibiotics, medication indication, medication timing, drug selection, usage and dosage, medication course, drug combination, etc. RESULTS: After the following intervention measures were adopted, such as The prophylactic utilization rate of antibiotics of our hospital during perioperative period of clean operation decreased from 96. 7％ before intervention to 25. 0％ after intervention (P< 0. 05). The rates of drug use without indication, irrational medication timing before surgery, irrational drug selection, irrational usage and dosage, irrational medication course and irrational drug combination were decreased from 71. 3％, 72. 4％, 65. 5％, 23. 0％, 97. 1％, 17. 8％ before intervention to 4. 4％, 0, 8. 9％, 11. 1％, 22. 2％, 0 after intervention (P<0. 05) respectively. Before intervention, 8 categories 20 kinds of antibiotics were used prophylactically in our hospital during perioperative period of clean operation; 86 patients used 2 kinds of or more antibiotics, among which there were 31 cases of drug combination and 55 cases of drug replacement. After intervention, 3 categories 4 kinds of antibiotics were used prophylactically in our hospital during perioperative period of clean operation; there was no drug combination and drug replacement. CONCLUSIONS: Special prescription comment model can obviously improve rational use of antibiotics during perioperative period of clean operation.关键词
清洁手术/围术期/抗菌药物/专项处方点评模式/干预Key words
Clean operation/Perioperative period/Antibiotics/Special prescription comment model/Intervention分类
医药卫生引用本文复制引用
程模,杨培洪,何霖..专项处方点评模式对我院清洁手术围术期抗菌药物预防使用的干预效果评价[J].中国药房,2018,29(3):293-297,5.基金项目
重庆市卫生和计划生育委员会医学科研项目(No. 2017MSXM193) （No. 2017MSXM193）
