中国药房2018，Vol.29Issue(3)：303-306,4.DOI:10.6039/j.issn.1001-0408.2018.03.04
芒柄花素包合物脂质体的制备及质量评价
Preparation and Quality Evaluation of Formononetin Inclusion Compound Liposome
摘要
Abstract
OBJECTIVE: To prepare Formononetin (FMN) inclusion compound liposome and evaluate its quality. METHODS: FMN inclusion compound liposome was prepared by film dispersion method. The morphology, particle size, Zeta potential, encapsulation efficiency and in vitro release properties were studied. RESULTS: The particle size, Zeta potential and encapsulation efficiency of prepared FMN inclusion compound liposome were (255. 34 ± 12. 87) nm, (25. 32 ± 3. 51) mV, (81. 63 ± 0. 79)％, respectively (n=3). The 24 h accumulative release rate of prepared FMN inclusion compound liposome was 56. 12％. CONCLUSIONS: FMN inclusion compound liposome with good sustained-release effect is prepared successfully and in line with related quality standard.关键词
芒柄花素/包合物/脂质体/质量评价Key words
Formononetin/Inclusion compound/Liposome/Quality evaluation分类
医药卫生引用本文复制引用
廖灿城,郭波红,许丹翘,吴秀君,易军,黄泽贤..芒柄花素包合物脂质体的制备及质量评价[J].中国药房,2018,29(3):303-306,4.基金项目
国家自然科学基金资助项目(No. 81403111) （No. 81403111）
