中国药房2018，Vol.29Issue(3)：349-352,4.DOI:10.6039/j.issn.1001-0408.2018.03.14
补肾养血颗粒的提取工艺优化研究
Study on Optimization of the Extraction Technology of Bushen Yangxue Granules
摘要
Abstract
OBJECTIVE: To optimize the extraction technology of Bushen yangxue granules, and to provide reference for developing hospital preparations. METHODS: The orthogonal test was designed to optimize the extraction technology of Bushen yangxue granules using the comprehensive score including the content of hyperoside and total flavonoids, extract yield as evaluation indexes, water amount, extraction time and extraction times as factors. Verification test was also conducted. RESULTS: The extraction technology of Bushen yangxue granules was 10-fold water, extracting for 2 times and 1 hour each time. The results of verification test indicated that the contents of hyperoside and total flavonoids were 0. 154 mg/g (RSD=0. 010％, n=3) and 11. 094 mg/g (RSD=0. 008％, n=3). The average extract yield was 37. 76％ (RSD=0. 008％, n=3). CONCLUSIONS: The optimized extraction technology is stable and feasible, which can provide the basis for developing hospital preparations of Bushen yangxue granules.关键词
补肾养血颗粒/提取工艺/金丝桃苷/总黄酮/正交试验Key words
Bushen yangxue granules/Extraction technology/Hyperoside/Total flavonoids/Orthogonal test分类
医药卫生引用本文复制引用
刘霞,杨敏,冷静,范智琴,徐冲..补肾养血颗粒的提取工艺优化研究[J].中国药房,2018,29(3):349-352,4.基金项目
重庆市科学技术委员会基本科研业务费计划项目(No. cstc2015jbky330025009) （No. cstc2015jbky330025009）
中药炮制技术传承基地建设项目 （）
