中国药房2018，Vol.29Issue(3)：374-377,4.DOI:10.6039/j.issn.1001-0408.2018.03.20
3种用药方案治疗甲状腺功能亢进的药物经济学评价
Pharmacoeconomic Evaluation of 3 Therapeutic Regimens for Hyperthyroidism
摘要
Abstract
OBJECTIVE: To evaluate the economical efficiency of 3 therapeutic regimens for hyperthyroidism. METHODS: Medical records of 564 hyperthyroid outpatients were selected from our hospital in 2016, and they were divided into group A (185 cases), group B(191 cases) and group C(188 cases) according to drug use. Group A received Thiamazole tablets 2-4 tablet, once asthecondition gradually reduce th amount to 0. 5-2 tablets orally; group B received Thiamazole tablets (cusage and dosage are the same as group A)+Yikang pills 6 g, bid orally; group C received Thiamazole tablets (cusage and dosage are the same as group A)+ Xiakucao tablets 6 tablets, bid orally. The treatment courses of 3 groups lasted for 10 months. Clinical efficacy the occurrence of ADR and recurrence were observed in 3 groups. The pharmacoeconomic cost-effectiveness analysis was adopted for the economic evaluation of 3 therapeutic regimens. RESULTS: The tolal response rates of group A, B, C were 94. 06％, 95. 29％, 95. 75％, respectively; total incidence of ADR were 11. 36％, 10. 48％, 10. 11％; there was no statistical significance (P>0. 05). No recurrence occurred in the 3 groups. The average cost of 3 groups were 633. 80, 3 548. 89, 3 596. 00 yuan, respectively. The cost of group A was the lowest. The results of sensitivity analysis were also that the cost of group A was the lowest. CONCLUSIONS: 3 therapeutic regimens show good therapeutic efficacy and safety for hyperthyroidism, among which thiamazole alone has relatively higher pharmacoeconomic significance.关键词
药物经济学/甲状腺功能亢进/甲巯咪唑片/抑亢丸/夏枯草片/最小成本分析Key words
Pharmacoeconomics/Hyperthyroidism/Thiamazole tablets/Yikang pills/Xiakucao tablets/Cost minimization analysis分类
医药卫生引用本文复制引用
唐哲,韦鞾,曹步清..3种用药方案治疗甲状腺功能亢进的药物经济学评价[J].中国药房,2018,29(3):374-377,4.基金项目
广西壮族自治区卫生和计划生育委员会自筹经费科研课题(No. Z20170059) （No. Z20170059）
