中国药房2018，Vol.29Issue(4)：458-460,3.DOI:10.6039/j.issn.1001-0408.2018.04.07
枳实药材乙醇提取物的化学成分研究
Study on Chemical Constituents of Ethanol Extract from Cirtus aurantium
摘要
Abstract
OBJECTIVE: To study the chemical constituents of ethanol extract from Cirtus aurantium. METHODS: The ethanol extract of C. aurantium was isolated and purified by silica gel column, open ODS column, preparation liquid chromatography, HW-40F gel column and macroporous resin column. The structure of compounds was analyzed and identified according to physicochemical properties and spectral data (mass spectrum, hydrogen spectrum, carbon spectrum). RESULTS: Eight compounds were isolated from ethanol extract of C. aurantium, i. e. Rimboxo (1), Thymidine (2), Uracil (3), Cyclo-(Leu1-Ile2-Ala3-Thr4-Gly5-Thr6-Phe7) (4), Cyclo- (Leu1-Leu2-Pro3-Tyr4-Gly5-Ser6-Pro7) (5), Meranzin hydrate-β-D-glucoside (6), Umbelliferone (7), Linaloyl glucoside (8). CONCLUSIONS: Compound 1, 2, 3, 8 are isolated from Citrus L. for the first time, compound 4, 5, 6 were isolated from C. aurantium for the first time. The study lays the foundation for quality evaluation of C. aurantium.关键词
枳实/化学成分/结构鉴定/乙醇提取物/柑橘属Key words
Cirtus aurantium/Chemical constituent/Structural identification/Ethanol extract/Citrus L.分类
医药卫生引用本文复制引用
邓可众,苌美燕,宗琪,熊英..枳实药材乙醇提取物的化学成分研究[J].中国药房,2018,29(4):458-460,3.基金项目
国家自然科学基金资助项目(No. 81260621) （No. 81260621）
