中国医科大学学报2018，Vol.47Issue(3)：198-201,4.DOI:10.12007/j.issn.0258-4646.2018.03.002
利用频域光学相干断层扫描分析高度近视患者黄斑区视网膜外核层厚度
Application of Spectral-domain Optical Coherence Tomography in the Measurement of the Macular Outer Nuclear Layer in Patients with High Myopia
摘要
Abstract
Objective To quantitatively analyze the difference in retinal thickness of the macular outer nuclear layer (ONL) between high myopia patients and normal subjects using spectral-domain optical coherence tomography (SD-OCT). Methods Seventy-eight participants (78 eyes) were divided into normal control group and high myopia group, according to the spherical equivalent (SE) of each eye. There were 24 cases (24 eyes) in the normal control group (-0. 25 D ～+0. 25 D) and 54 cases (54 eyes) in the high myopia group(SE＜-6. 00 D). The macular retina was scanned using the posterior pole asymmetry analysis mode of the Heidelberg Spectralis (SD-OCT) system and divided into 9 areas according to Early Treatment of Diabetic Retinopathy Study. Quantitative analysis was performed to compare the difference in retinal thickness of the macular ONL in each area between the high myopia and normal control groups. Results The ONL thickness in the central area of the macular retina was significantly higher than that in the superior, nasal, inferior, and temporal areas (P ＜ 0. 001 for all comparisons). The ONL thickness in the inferior area of the macular retina was significantly lower than that in the central, superior, nasal, and temporal areas (P ＜ 0. 001 for all comparisons). In other sub-regions, no difference in the ONL thickness was found. The ONL thickness in the central, superior, nasal, inferior, and temporal areas was significantly lower in the high myopia group than in the normal control group (P ＜ 0. 05 for all comparisons). Conclusion Regional variation is observed in the ONL thickness. The ONL thickness in the macular area of patients with high myopia is thinner.关键词
外核层/光学相干断层扫描/高度近视/视网膜厚度Key words
outer nuclear layer/optical coherence tomography/high myopia/retinal thickness分类
医药卫生引用本文复制引用
陈禹橦,刘贤洁,刘美丹,马小力..利用频域光学相干断层扫描分析高度近视患者黄斑区视网膜外核层厚度[J].中国医科大学学报,2018,47(3):198-201,4.基金项目
国家自然科学基金(81200656) （81200656）
辽宁省自然科学基金(201602844) （201602844）
