中国药理学通报2018,Vol.34Issue(7):892-894,3.DOI:10.3969/j.issn.1001-1978.2018.07.002
前动力蛋白2在心血管病变中的研究进展
Progress of prokineticin 2 in cardiovascular diseases
摘要
Abstract
Cardiovascular diseases are characterized by cardiac and vascular dysfunction. Prokineticin 2 ( PK2 ) is a newly found secretory peptide which plays a key role in the physiology homeostasis via prokineticin receptor 1 and 2 ( PKR1 and 2). Furthermore, PK2/PKR1 signaling pathway plays an important role in protecting cardiovascular diseases. Here we discuss the effect of PK2/PKR1 signaling in myocardial infarction, conges-tive heart failure and vascular endothelial dysfunction.关键词
前动力蛋白2/PKR1/PKR2/心肌梗死/心衰/血管内皮功能紊乱Key words
prokineticin 2/prokineticin receptor 1/prokineti-cin receptor 2/myocardial infarction/congestive heart failure/vascular endothelial dysfunction分类
医药卫生引用本文复制引用
黄聪,郭敏,陈娟,蔡飞,张又枝..前动力蛋白2在心血管病变中的研究进展[J].中国药理学通报,2018,34(7):892-894,3.基金项目
国家自然科学基金资助项目( No 81603110) ( No 81603110)
湖北省教育厅青年基金资助项目( No Q20152802) ( No Q20152802)
湖北科技学院药学重点学科专项科研项目资助(No 2018-19XZY15) (No 2018-19XZY15)