中国药理学通报2018，Vol.34Issue(7)：903-906,4.DOI:10.3969/j.issn.1001-1978.2018.07.005
斑马鱼在药学领域的应用研究
Application of zebrafish in field of pharmacy
摘要
Abstract
Zebrafish (Danio rerio) is a simple biological labora-tory animal, with similar biological structure and physiological functions to mammals. Almost transparent embryos, in vitro de-velopment of embryos and up to 87% of human genetic similari- ties enable a wide application of zebrafish in the field of pharma-ceutical research. In this paper, we have studied the application of zebrafish in drug metabolism, the research of Chinese medi-cine, the evaluation of drug toxicology and safety, the screening of drugs and the discovery of new drugs, the research of regener- ative drugs, so as to provide new ideas of zebrafish in the field of pharmacy.关键词
斑马鱼/药物代谢/中药/毒理学/药物筛选/再生药物/应用Key words
zebrafish/drug metabolism/traditional Chinese medicine/toxicology/drug screening/regenerative drugs/ap-plication分类
医药卫生引用本文复制引用
祁美娟,石美智,韩永龙..斑马鱼在药学领域的应用研究[J].中国药理学通报,2018,34(7):903-906,4.基金项目
国家自然科学基金面上项目(No:81773949) （No:81773949）
浦东新区科技发展基金民生科研专项资金(No:PKJ2017-Y07) （No:PKJ2017-Y07）
浦东新区卫生计生科技项目卫生行业科研专项(No:PW2017E-2) （No:PW2017E-2）
上海市第六人民医院东院院级科学研究基金( No 2016018) （ No 2016018）
