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Box-Behnken响应面法优化青龙衣中胡桃醌提取工艺

王丽红 闫勇杰 赵宏 宗希明 张云杰

中国中医药信息杂志2018,Vol.25Issue(7):67-70,4.
中国中医药信息杂志2018,Vol.25Issue(7):67-70,4.DOI:10.3969/j.issn.1005-5304.2018.07.016

Box-Behnken响应面法优化青龙衣中胡桃醌提取工艺

Optimization of Extraction Process for Walnut Quinone from Juglans Green Peel by Box-Behnken Response Surface

王丽红 1闫勇杰 1赵宏 1宗希明 1张云杰1

作者信息

  • 1. 佳木斯大学药学院,黑龙江 佳木斯 154007
  • 折叠

摘要

Abstract

Objective To optimize extraction process of walnut quinone from Juglans green peel. Methods On the basis of single factor tests, taking material-liquid ratio, extracting temperature and ethanol concentration as independent variables, yield of walnut quinone in response to as a value, according to Box-Behnken experiment design principle, extraction process of walnut quinone from Juglans green peel was optimized by response surface analysis. Results The optimum extraction process of walnut quinone was: 14.30 times the amount of 89.81% ethanol;30.28 ℃ constant temperature. The extracting amount of walnut quinone was 2.034 mg/g, which was close to the experimental results of 1.957 mg/g. Conclusion The optimized extraction process is reasonable and feasible, which can provide reference for the extraction of walnut quinone from Juglans green peel.

关键词

青龙衣/Box-Behnken响应面法/核桃楸/胡桃醌/提取工艺

Key words

Juglans green peel/Box-Behnken response surface methodology/Juglans mandshurica/walnut quinone/extraction process

分类

医药卫生

引用本文复制引用

王丽红,闫勇杰,赵宏,宗希明,张云杰..Box-Behnken响应面法优化青龙衣中胡桃醌提取工艺[J].中国中医药信息杂志,2018,25(7):67-70,4.

基金项目

黑龙江省教育厅基本科研业务费项目(2016-KYYWF-0584) (2016-KYYWF-0584)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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