中华骨质疏松和骨矿盐疾病杂志2018，Vol.11Issue(3)：317-322,6.DOI:10.3969/j.issn.1674-2591.2018.03.015
肠道菌群与骨骼代谢
Gut microbiota and bone metabolism
摘要
Abstract
Gut microbiota (GM) is the microflora colonized in the intestinal tract. Recently, more and more study identified the regulated effects of GM on bone metabolism, the mechanism of which mainly includes regulating calci-um absorption, affecting osteoclasts number and function through modulating immune system, exerting roles on secretion of intestinal hormones. Probiotics and prebiotics have a protection on bone through regulating GM spectrum. Therefore, GM will be a therapeutic target of osteoporosis and other bone diseases. Moreover, probiotics and prebiotics will provide a new treatment to osteoporosis.关键词
肠道菌群/益生菌/益生元/骨骼Key words
gut microbiota/probiotics/prebiotics/bone分类
医药卫生引用本文复制引用
李路娇,李梅..肠道菌群与骨骼代谢[J].中华骨质疏松和骨矿盐疾病杂志,2018,11(3):317-322,6.基金项目
国家自然科学基金面上项目 (81570802) （81570802）
中国医学科学院医学与健康科技创新工程项目 (2016-I2M-3-003) （2016-I2M-3-003）
国家重点研发计划 (2016YFC0901501) （2016YFC0901501）
