浙江医学2018，Vol.40Issue(9)：956-958,3.DOI:10.12056/j.issn.1006-2785.2018.40.9.2017-1094
嗜酒患者无痛胃镜检查时丙泊酚用量与效果观察
Dosage and effect of propofol during painless gastroscopic examination for alcoholic patients
摘要
Abstract
Objective To observe the dosage and effect of propofol during the painless gastroscopic examination for alcoholic patients. Methods One hundred and twenty seven patients underwent painless gastroscopic examination, including 63 alcoholic patients(alcoholic group) and 64 non-alcoholic patients (non-alcoholic group). Propofol(1.3mg/kg) was intravenously injected for 20 seconds after fentanyl (0.7μg/kg) was given. When the eyelash areflexia appeared the gastroscopy was performed. SAS was used to assess the sedative level of patients during gastroscopic examination; and when the total score of SAS was over 4 points, propofol was added as appropriate. Results There was no significant difference in the time of gastroscopy between two groups (P ＞0.05). Patients in alcoholism group had higher SAS scores at T1 (1min after administration) and T2 (after the inspection) (both P＜0.05) than those in non-alcoholic group. The times of propofol superaddition in the alcoholic group was more than that in non-alcoholic group (P＜0.05). The cumulative dosage of propofol and the frequency of cumulative propofol amount over 150 mg in the alcoholics group were higher than those in the non-alcoholism group (both P＜0.05). The SBP, DBP in T1 and the HR in T2 in the alcoholics group were higher than those in the non-alcoholic group(both P＜0.05). Conclusion Both the times of propofol superaddition and the cumulative dosage of propofol for alcoholic patients are more than those for non-alcoholic patients in painless gastroscopic examination.关键词
嗜酒/无痛胃镜/丙泊酚/效果Key words
Alcohol addiction/Painless gastroscopy/Propofol/Effect引用本文复制引用
陈敏芳,冀子中,邵菁,谢丽萍,刘学英,刘建迪,郁慧杰,王黎梅,孔月华,胡冬兰,金慧文..嗜酒患者无痛胃镜检查时丙泊酚用量与效果观察[J].浙江医学,2018,40(9):956-958,3.基金项目
嘉兴市科技计划项目(2012AY1070-10) （2012AY1070-10）
