浙江医学2018，Vol.40Issue(10)：1059-1061,3.DOI:10.12056/j.issn.1006-2785.2018.40.10.2018-679
超声引导下聚桂醇联合甲氨蝶呤孕囊注射治疗剖宫产瘢痕妊娠的疗效观察
Efficacy and safety of ultrasound-guided gestational sac injection of lauromacrogol and methotrexate for cesarean scar pregnancy
孟迪云 1杜英 1任月芳 1刘明松2
作者信息
- 1. 313000 湖州市妇幼保健院妇产科
- 2. 313000 湖州市妇幼保健院超声科
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of ultrasound-guided gestational sac injection of lauromacrogol and methotrexate (MTX) for cesarean scar pregnancy (CSP). Methods Sixty-nine women with CSP were randomly divided into the study group (36 cases) and the control group (33 cases). In study group, the lauromacrogol and MTX (50mg) were injected into gestation sac guided by ultrasound, and in the control group the MTX (50mg) was injected. The curettage was performed under ultrasonic monitoring in two groups 24h after injection. The volume of intraoperative bleeding, the proportion of Foley catheter balloon placement, the recovery time of blood β -HCG level, the thickness of the uterine scar wall, the time of menstruation recovery, the adverse reactions were documented and compared between two groups. Results The volume of intraoperative bleeding and the proportion of Foley catheter balloon placement and the incidence of adverse reactions in study group were lower, the recovery time of blood β -HCG and the recovery time of menstruation were shorter than those in the control group(all P＜0.05). There was no significant difference in the thickness of the uterine scar wall 3 months after the operation between two groups (P ＞0.05). Conclusion Ultrasound-guided gestational sac injection of lauromacrogol combined with methotrexate for CSP is safe and less invasive with less adverse reactions, it can be applied in primary hospitals.关键词
超声介入/聚桂醇/甲氨蝶呤/清宫术/剖宫产瘢痕妊娠Key words
Ultrasonic intervention/Lauromacrogol/Methotrexate/Curettage/Cesarean scar pregnancy引用本文复制引用
孟迪云,杜英,任月芳,刘明松..超声引导下聚桂醇联合甲氨蝶呤孕囊注射治疗剖宫产瘢痕妊娠的疗效观察[J].浙江医学,2018,40(10):1059-1061,3.
