张玲 1张泉修 1刘艳丽 1许琼明 1杨世林 1毛晨梅2
作者信息
- 1. 苏州大学药学院,江苏 苏州 215123
- 2. 苏州大学附属儿童医院,江苏 苏州 215000
- 折叠
摘要
Abstract
To investigate the chemical constituents from Ilex pubescens var. kwangsiensis roots. Methods: All the compounds were isolated and purified by repeated column chromatography on silica gel,ODS,Sephadex LH-20,medium pressure column chromatography,high pressure flash chromatography and semi-preparative HPLC,and their structures were elucidated on the basis of physico-chemical constants and spectral analysis. Results: 16 compounds were isolated and identified as butyl isolignstroside(1), liguside B(2), isoligustroside(3), oleonuezhenide(4),(2″R) -2″-methoxyoleuropein(5),(2″S) -2″-methoxyoleuropein(6), jasurolignoside (7), oleuropein-3″-methyl ether(8), isoacteoside(9), vanillyl-β-D-glucopyranoside(10),hebeoside(11),(-) -olivil(12),pinnatifidanin B Ⅱ(13), sinapic aldehyde 4-O-β-D-glucopyranoside(14), torenoside B(15) and sinenoside I(16). Conclusion: Compounds 1～ 3, 5～ 9, 11, 13, 15 and 16 are obtained from this genus for the first time, and all the compounds are obtained from this plant for the first time.关键词
广西毛冬青/化学成分Key words
Ilex pubescens Hook. et Arn. var. kwangsiensis Hand. -Mazz./Chemical constituents分类
医药卫生
