组织工程与重建外科杂志2018，Vol.14Issue(3)：143-147,5.DOI:10.3969/j.issn.1673-0364.2018.03.007
肢体部葡萄酒色斑血流灌注量与脉冲染料激光治疗效果的关系:前瞻性自身对照研究
Correlation Analysis Between Blood Perfusion and Pulsed Dye Laser(PDL)Effectiveness of Port-Wine Stains(PWS)on Extremities:A Prospective Self-Control Study
摘要
Abstract
Objective To explore the relationship between blood perfusion and pulsed dye laser(PDL)effectiveness of port-wine stains(PWS)on extremities.Methods Patients with untreated PWS on extremities were selected.Blood perfusion of the selected sites on both proximal and distal limbs as well as control sites was detected by laser speckle image(LSI)before treatment.Then the patients were treated with PDL for 3 sessions in total.After 3 months of treatment,the therapeutic effect was evaluated,and the relationship between blood perfusion and therapeutic effect was analyzed.Results Nineteen patients were included,17 on upper limb and 2 on lower limb.The mean Speckle Flow Image(SFI)value of the PWS on upper arm/thigh was significantly lower(80.51 ±16.96)PU than the SFI on hand/feet(155.68 ±71.86)PU.According to photometric evaluation and VAS score,the PDL efficacy on proximal limbs was significantly better than distal limbs(P<0.05).Significant correlations existed between blood perfusion and PDL efficacy(r=-0.351,P=0.031).Conclusion PWS on the proximal limb responds better to PDL,compared with PWS on the distal limb.This variation in efficacy may attribute to differences in blood perfusion.关键词
葡萄酒色斑/脉冲染料激光/血流灌注量/流速/散斑成像Key words
Port-wine stains/Pulsed dye laser/Blood flow/Perfusion/Speckle flow imaging分类
医药卫生引用本文复制引用
朱佳芳,马刚,于文心,王天佑,陈怡洁,常雷,林晓曦..肢体部葡萄酒色斑血流灌注量与脉冲染料激光治疗效果的关系:前瞻性自身对照研究[J].组织工程与重建外科杂志,2018,14(3):143-147,5.基金项目
国家自然科学基金青年项目(81602777). （81602777）
