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血液灌流联合连续性静脉-静脉血液滤过在急性有机磷农药中毒救治中的应用观察

袁磊

国际医药卫生导报2018,Vol.24Issue(13):2020-2022,3.
国际医药卫生导报2018,Vol.24Issue(13):2020-2022,3.DOI:10.3760/cma.j.issn.1007-1245.2018.13.034

血液灌流联合连续性静脉-静脉血液滤过在急性有机磷农药中毒救治中的应用观察

Hemoperfusion combined with continuous veno-venous hemofiltration in the treatment of acute organophosphorus pesticide poisoning

袁磊1

作者信息

  • 1. 476400 商丘,夏邑县人民医院急诊科
  • 折叠

摘要

Abstract

Objective To observe the effect of hemoperfusion (HP) combined with continuous venovenous hemofiltration (CVVH) in the treatment of acute organophosphorus pesticide poisoning (AOPP).Methods Eighty-two patients with AOPP admitted to our hospital from May 2015 to May 2017 were selected and were randomly divided into control group and study group,41 cases in each group.The patients in the control group were treated with HP,and the patients in the study group were treated with HP+CVVH.The survival rate and the survival time of the died patients of the two groups were compared,as well as the levels of whole blood cholinesterase and inflammatory factors before and after treatment.Results There were no statistically significant differences in the survival rate,whole blood cholinesterase before and after treatment,and the levels of TNF-α and IL-6 before treatment between the two groups (P>0.05).The survival time of the died patients of the study group was longer than that of the control group,the levels of TNF-α and IL-6 of the study group after treatment were lower than those of the control group,with statistically significant differences (P<0.05).Conclusion HP combined with CVVH can effectively prolong the survival time of patients and reduce the degree of inflammatory response after poisoning.

关键词

急性有机磷农药中毒/血液灌流/连续性静脉-静脉血液滤过

Key words

Acute organophosphorus pesticide poisoning/Hemoperfusion/Continuous veno-venous hemofiltration

引用本文复制引用

袁磊..血液灌流联合连续性静脉-静脉血液滤过在急性有机磷农药中毒救治中的应用观察[J].国际医药卫生导报,2018,24(13):2020-2022,3.

国际医药卫生导报

1007-1245

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