国际医药卫生导报2018,Vol.24Issue(13):2031-2033,3.DOI:10.3760/cma.j.issn.1007-1245.2018.13.038
万古霉素缓释系统与Wright硫酸钙治疗创伤后骨折内固定术后骨感染的治疗效果探讨
The therapeutic effect of vancomycin sustained release system and Wright calcium sulfate in the treatment of bone infection after internal fixation for posttraumatic fracture
张金刚 1刘大伟 1宋思桐 1高洪达 1胡海平 1李爽2
作者信息
- 1. 154000 佳木斯市中心医院骨外一科
- 2. 154000 佳木斯大学附属第一医院呼吸内科
- 折叠
摘要
Abstract
Objective To explore the therapeutic effect of vancomycin sustained release system and Wright calcium sulfate in the treatment of bone infection after internal fixation for posttraumatic fracture.Methods 68 patients with bone infection after internal fixation for posttraumatic fracture were selected as the object of this study from our hospital from March 2016 to June 2017,and were randomly divided into control group and observation group.The patients in the control group were treated with intravenous injection of sensitive antibiotics,and the patients in the observation group were treated with vancomycin sustained release system and Wright calcium sulfate.The therapeutic effect and various indexes of the two groups were compared.Results The fracture healing time and bone cavity healing time in the observation group were shorter than those in the control group (P<0.05).The infection clearance rate,re-operation rate,and fracture healing rate in the observation group were superior to those in the control group (P<0.05).Conclusion Vancomycin sustained release system and Wright calcium sulfate in the treatment of bone infection after internal fixation for posttraumatic fracture can not only accelerate the healing of fracture and bone cavity,improve the infection clearance rate,and reduce the probability of re-operation to a certain extent.关键词
万古霉素缓释系统/Wright硫酸钙/骨感染/骨折内固定术Key words
Vancomycin sustained release system/Wright calcium sulfate/Bone infection/Fracture internal fixation引用本文复制引用
张金刚,刘大伟,宋思桐,高洪达,胡海平,李爽..万古霉素缓释系统与Wright硫酸钙治疗创伤后骨折内固定术后骨感染的治疗效果探讨[J].国际医药卫生导报,2018,24(13):2031-2033,3.