中国感染控制杂志2018，Vol.17Issue(3)：252-255,4.DOI:10.3969/j.issn.1671-9638.2018.03.014
葡萄糖酸氯己定擦浴预防ICU患者多重耐药菌感染
Prevention of multidrug-resistant organism infection through chlorhexidine gluconate rubbing bathing in patients in intensive care unit
黄劲华 1孔旭辉 1丁滢 1朱铁林 1王玲1
作者信息
- 1. 泰州市人民医院,江苏 泰州 225300
- 折叠
摘要
Abstract
Objective To study the effect of chlorhexidine gluconate rubbing bathing on preventing multidrug-resistant organism(MDRO)infection in patients in intensive care unit(ICU).Methods 108 critically ill patients in a tertiary first-class hospital between January and December 2016 were randomly divided into trial group and control group.Trial group adopted wet towel containing 2％ chlorhexidine gluconate for bathing, control group adopted water for bathing.Bacteriostasis rate, incidence of healthcare-associated infection(HAI), occurrence of MDRO infection, and adverse reaction between two groups of patients after rubbing bathing were compared.Results There was no significant difference in the bacteriostasis rate within 2 hours between two groups(P＞0.05), bacteriostasis rates of trial group after 4, 8, and 24 hours of bathing were significantly higher than control group(P＜0.001).Incidences of HAI in trial group and control group were 44.44％(24/54)and 66.67％(36/54)respectively(P＜0.05); incidences of MDRO infection in trial group and control group were 20.37％(11/54)and 40.74％(22/54)respectively(P＜0.05).The main infection sites in trial group and control group were both lower respiratory tract, accounting for 87.50％and72.22％respectively;8 cases(33.33％)in trial group and11(30.55％)in control group had ventilator-associated pneumonia(VAP).11 strains of MDROs in trial group and 22in control group were isolated, both were mainly carbapenem-resistant Acinetobacter baumannii (CRAB).There was no adverse reaction after the bathing in both groups.Conclusion Application of chlorhexidine gluconate bathing can effectively reduce the incidence of HAI and MDRO infection in ICU patients.关键词
氯己定/ICU/多重耐药菌/医院感染Key words
chlorhexidine/intensive care unit/multidrug-resistant organism/healthcare-associated infection分类
医药卫生引用本文复制引用
黄劲华,孔旭辉,丁滢,朱铁林,王玲..葡萄糖酸氯己定擦浴预防ICU患者多重耐药菌感染[J].中国感染控制杂志,2018,17(3):252-255,4.
