中国现代医学杂志2018，Vol.28Issue(19)：62-66,5.DOI:10.3969/j.issn.1005-8982.2018.19.012
结肠镜检查人群肛门HPV感染情况调查及危险因素分析
Investigation of HPV infection and analysis of risk factors in colonoscopy
摘要
Abstract
Objective To investigate the infection of Human Papillomavirus (HPV) in human colon by colonoscopy and to analyze the risk factors of anal HPV infection. Methods A total of 273 patients who underwent colonoscopy at the Endoscopic Center of the First Affiliated Hospital of Xinjiang Medical University from November 2014 to November 2016 were investigated by questionaires. The epidermal cells were collected by anal brush and the pathological changes were observed under microscope. HC2 method combined gene chip method was used for detection and genotyping of HPV-DNA. Results Of the 273 samples, 8 were positive for HPV-DNA, the total infection rate was 2.93%. Among them, 4 were type (52+58), 2 were type 16, 1 was type 35 and 1 was type 39, all belonged to high-risk types of HPV. No obvious pathological changes were observed under microscope. Age, educational level and gastrointestinal symptoms were the independent risk factors for anal HPV infection. Conclusions There is a certain HPV infection rate in the people receiving colonoscopy. Age, educational level and gastrointestinal symptoms are the independent risk factors for anal HPV infection.关键词
人类乳头状病毒/肛门/危险因素Key words
Human Papillomavirus/anus/risk factor分类
医药卫生引用本文复制引用
唐湘嫘,张志强,夏宇..结肠镜检查人群肛门HPV感染情况调查及危险因素分析[J].中国现代医学杂志,2018,28(19):62-66,5.基金项目
新疆维吾尔自治区自然科学基金项目(No :2014211C052) （No :2014211C052）
新疆维吾尔自治区重大科技专项计划(No :201430123-1) （No :201430123-1）
