中国现代医学杂志2018，Vol.28Issue(19)：67-74,8.DOI:10.3969/j.issn.1005-8982.2018.19.013
急性主动脉夹层发生低氧血症患者危险因素的Meta分析
A meta-analysis of risk factors for hypoxemia in patients with acute aortic dissection
摘要
Abstract
Objective To identify the risk factors of hypoxemia in patients with acute aortic dissection by a meta-analysis. Methods Electronic literature databases in Chinese and English and references of included studies were searched. Those studies were independently screened by two evaluation persons in accordance with the standard, the information was extracted, the quality of studies was assessed in term of study design, meta-analysis was conducted by RevMan 5.0. Results Totally 7 studies were identified from 27 papers including 1,175 cases. There were 376 cases of hypoxemia and 799 cases of non-hypoxemia in the patients with aortic dissection. A total of 63 risk factors were involved; only BMI >25 kg/m2, PaO2/FiO2 ratio ≤300 mmHg, CPB time, prolonged mechanical ventilation and ICU stay time were identified as the predictive factors for hypoxemia in the patients with acute aortic dissection; and interventional therapy was identified as the protective factor for aortic dissection. Conclusions Our results suggest that BMI >25 kg/m2, PaO2/FiO2 ratio ≤300 mmHg, CPB time, prolonged mechanical ventilation, and ICU stay time are the risk factors for hypoxemia in the patients with acute aortic dissection. Postoperative hypoxemia is a common complication in the patients treated by aortic dissection surgery. Its risk factors are affected by many factors. Therefore, a large number of prospective and high-quality studies are still needed.关键词
急性主动脉夹层/低氧血症/危险因素/Meta分析Key words
acute aortic dissection/hypoxemia/risk factor/meta-analysis分类
医药卫生引用本文复制引用
张欢欢,杨玉金,张加乐,郑春艳,朱剑,李霏..急性主动脉夹层发生低氧血症患者危险因素的Meta分析[J].中国现代医学杂志,2018,28(19):67-74,8.基金项目
江西省科技计划项目(No :20151BBG70180) （No :20151BBG70180）
