国际病理科学与临床杂志2018，Vol.38Issue(3)：485-489,5.DOI:10.3978/j.issn.2095-6959.2018.03.004
子宫内膜细胞蜡块切片在子宫内膜癌早期诊断的应用
Application of endometrial cell wax block examination in early diagnosis of endometrial cancer
陈雪 1周炳娟 1孙吉瑞 1张丙信 1乔海芝 1张金库1
作者信息
- 1. 保定市第一中心医院病理科,河北 保定 071000
- 折叠
摘要
Abstract
Objective: To study the clinical application of endometrial cell block examination in early diagnosis of endometrial cancer and other diseases. Methods: From June to December of 2016, specimens of 80 patients from gynecological clinic at risk for developing endometrial cancer were examined. Endometrial cells were brushed, fixed by 95％ alcohol, embedded by paraffin, sliced up and HE stained. The diagnosis of specimens obtained through curettage was regarded as diagnostic standard, and analyzed the diagnostic accordance rate of endometrial cell block screening for endometrial cancer and benign endometrial lesions. Results: Endometrial cell block examination demonstrated a sensitivity of 83.33％ for endometrial cancer and 79.31％ for benign endometrial lesions. The specificity of endometrial cell block examination were 98.21％ for endometrial cancer and 96.08％ for benign endometrial lesions. The positive predictive value, negative predictive value and diagnostic efficiency were 95.23％, 93.22％ and 93.75％ for endometrial cancer. The positive predictive value, negative predictive value and diagnostic efficiency were 92.00％, 89.09％ and 90.00％ for benign endometrial lesions. Conclusion: Endometrial cell block examination is a simple, safe and reliable method for early diagnosis of endometrial lesions.关键词
细胞蜡块/子宫内膜癌/HE染色Key words
endometrial cell block/endometrial cancer/HE staining引用本文复制引用
陈雪,周炳娟,孙吉瑞,张丙信,乔海芝,张金库..子宫内膜细胞蜡块切片在子宫内膜癌早期诊断的应用[J].国际病理科学与临床杂志,2018,38(3):485-489,5.
