临床与病理杂志2018，Vol.38Issue(3)：504-508,5.DOI:10.3978/j.issn.2095-6959.2018.03.007
骨髓增生异常综合征患者胸骨与髂骨骨髓形态学比较
Comparison of bone marrow morphology between sternum and iliac bone in myelodysplastic syndrome patients
摘要
Abstract
Objective: To investigate the differences of bone marrow morphology between sternum and iliac bone in patients with myelodysplastic syndromes (MDS), and to evaluate the role of sternum examination in the diagnoses of MDS. Methods: Twenty-one patients who underwent sternum and iliac bone marrow aspiration and were diagnosed as MDS in our hospital from January 2015 to December 2015 were retrospectively analyzed. The cellularity, blast counts, typical dysplastic cells between sternum and iliac bone, and the impact on the diagnosis were compared. Results: The diagnostic rate of MDS was significantly higher with sternum examination than that with iliac bone. Myeloid cell percentage, myeloid erythroid ratio, blast percentage of excess blasts (EB) subtype in sternum ilium morphology were higher than those in iliac bone; by sternum examination, patients had more typical dysplastic erythroid cells. The chromosome examination success rate and the international prognostic scoring system (IPSS) score in EB subtype were higher in ilium sternum aspiration than that in iliac bone. Conclusion: Compared with iliac bone, sternal bone marrow aspiration could detect more dysplastic hematopoiesis and increased blasts and it may provide more help for the diagnoses, risk stratification of MDS.关键词
骨髓象/骨髓增生异常综合征/胸骨/髂骨Key words
bone marrow morphology/myelodysplastic syndrome/sternum bone/iliac bone引用本文复制引用
汪春晓,李海艳,张明,张福明,孟莹,何华,高素君,谭业辉..骨髓增生异常综合征患者胸骨与髂骨骨髓形态学比较[J].临床与病理杂志,2018,38(3):504-508,5.基金项目
吉林省卫生厅课题(2013Z086).This work was supported by the Health Department of Jilin Province, China (2103Z086). （2013Z086）
