临床与病理杂志2018,Vol.38Issue(3):659-663,5.DOI:10.3978/j.issn.2095-6959.2018.03.033
细胞自噬与神经退行性疾病机制的研究进展
Advances in mechanisms of autophagy and neurodegenerative diseases
摘要
Abstract
Autophagy is a unique process of lysosomal pathway of eukaryotic cells to degrade intracellular metabolites and autophagy dysfunction is closely related to neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's syndrome (PD). Regulating autophagy can effectively remove the protein from abnormal accumulation in the nervous system and alleviate the disease progression from the cellular level. Thus, autophagy may be an effective strategy and approach for treating neurodegenerative diseases.关键词
细胞自噬/神经退变性疾病/α-突触蛋白/β-淀粉样蛋白Key words
autophagy/neurodegenerative/α-synuclein/amyloid β-protein引用本文复制引用
冯会超..细胞自噬与神经退行性疾病机制的研究进展[J].临床与病理杂志,2018,38(3):659-663,5.基金项目
2014 年河北省政府资助临床医学优秀人才培养项目.This work was supported by the Hebei Provincial Government Foundation of Excellent Talent Training Grogram for Clinical Medicine 2014, China. ()