中医药导报2018，Vol.24Issue(8)：109-112,4.
温心汤对冠心病缓慢性心律失常患者心脏自主神经功能的影响
Effect of Wenxin Decoction(温心汤) on Cardiac Autonomic Nervous Function in Coronary Heart Disease Patients with Tardy Arrhythmia
摘要
Abstract
Objective: To investigate the effect of Wenxin decoction on cardiac autonomic nervous function in coronary heart disease (CHD) patients with tardy arrhythmia. Methods: A total of 152 CHD patients with tardy arrhythmia were divided into the control group and the treatment group by random number table, with 76 cases in each group. The control group took captopril, isosorbide mononitrate and enteric coated aspirin, while the treatment group took Wenxin decoction. The changes of clinical symptoms, average heart rate of dynamic electrocardiogram, minimum heart rate (MiHR), instant heart rate and heart rate variability (HRV) indexes [standard deviation of NN intervals (SDNN), standard deviation of average 5min NN intervals (SDANN), square root of the mean squared differences NN intervals (RMSSD), low frequency/high frequency (LF/HF)] of two groups before and after treatment were compared, and clinical efficacy and safety of two groups were evaluated. Results: The total effective rate of the treatment group was 92.11％, which was higher than 73.68％ of the control group (P＜0.05). Compared with pre-treatment, the TCM symptom scores, SDANN and RMSSD of two groups decreased after treatment, but average heart rate, MiHR, instant heart rate, SDNN and LF/HF increased, and above indexes of the treatment group were better than the control group (P＜0.05). There was no abnormal liver function, renal function and adverse reactions in two groups during treatment. Conclusion: Wenxin decoction for CHD patients with tardy arrhythmia can significantly increase clinical efficacy, relieve clinical symptoms, improve cardiac autonomic nervous function and promote body recovery, which has significance of clinical promotion.关键词
缓慢性心律失常/冠心病/温心汤/心脏自主神经功能/临床疗效Key words
trady arrhythmia/coronary heart disease/Wenxin decoction/cardiac autonomic nervous function/clinical efficacy分类
医药卫生引用本文复制引用
魏珍珍,盖海云,韩勇..温心汤对冠心病缓慢性心律失常患者心脏自主神经功能的影响[J].中医药导报,2018,24(8):109-112,4.基金项目
陕西省社会发展科技攻关项目(2015SF233) （2015SF233）
