基础医学与临床2018,Vol.38Issue(2):237-240,4.
IncRNA-CCATl与消化道肿瘤关系的研究进展
Progress on the relationship between lncRNA-CCATl and gastrointestinal cancer
摘要
Abstract
Colon cancer associated transcript 1 (CCAT1) is a kind of long non-coding RNA (IncRNA) found re-cently, which is aberrant overexpression in colorectal cancer, and it can promote cancer cell proliferation, invasion and metastasis. CCAT1 involves in the regulation of multiple pathophysiological processes, especially the formation and progression of gastrointestinal cancer, through the interaction with microRNA (miRNA) or protein by regulation mechanism like endogenous competition, and it is expected to serve as a valuable biomarker and therapeutic target.关键词
长链非编码RNA/结肠癌相关转录因子1/消化道肿瘤Key words
IncRNA/CCAT1/gastrointestinal cancer分类
医药卫生引用本文复制引用
李景林,郑汪洋,李鑫恒,李正龙,王志东,崔云甫,姜兴明..IncRNA-CCATl与消化道肿瘤关系的研究进展[J].基础医学与临床,2018,38(2):237-240,4.基金项目
国家自然科学基金(81602088) (81602088)
黑龙江省卫生计生委科研课题(2016-049) (2016-049)
黑龙江省博士后资助课题(LBH-Z16096) (LBH-Z16096)
哈尔滨医科大学创新 科学研究基金(2016LCZX09) (2016LCZX09)