中国当代医药2018，Vol.25Issue(16)：12-15,4.
高频重复经颅磁刺激对精神分裂症患者阴性症状改善作用持续性的随访研究
Follow-up study of high frequency repetitive transcranial magnetic stimulation on sustainability of the improvement role for negative symptoms in schizophrenic patients
摘要
Abstract
Objective To investigate the sustainability of high frequency repetitive transcranial magnetic stimulation on sustainability of the improvement role for negative symptoms in schizophrenic patients with chronic course of disease. Methods From September 2015 to September 2016,40 patients with negative symptoms of chronic schizophrenia hospitalized in Mental Hospital of Daxing District in Beijing City were selected.High frequency repetitive transcranial magnetic stimulation was used for treatment.Data were collected before treatment,end of treatment,1,3 months and 6 months after treatment.Positive and negative symptom scale (PANSS) and side effects scale (TESS) were used to evaluate efficacy and side effects.Results The difference between the negative symptom scores and the total score data in the PANSS scale before treatment,at the end of treatment,1,3 months and 6 months after treatment were statistically significant (F=45.621,57.369,P＜0.05).The results of q test showed that the values at the end of treatment and 1 months after treatment were all lower than those before treatment,after the end of treatment 3,6 months,the differences were statistically significant (P＜0.05).Before treatment,there were 2 cases of "tremor" patients and 1 case of "cast" patients,there was no significant change in symptoms after treatment.There was no statistical significance in the difference of severity score data in the TESS scale of different time points (F=1.254,P＜0.05).Conclusion High frequency repetitive transcranial magnetic stimulation treating schizophrenia can improve their clinical symptoms in the short term.In particular,the negative symptoms have been improved greatly,but the effect of the improvement will be gradually weakened due to the prolongation of the time,continuous treatment is recommended.关键词
重复经颅磁刺激/精神分裂症/阴性症状/随访Key words
Repetitive transcranial magnetic stimulation/Schizophrenia/Negative symptoms/Follow-up分类
医药卫生引用本文复制引用
蔡广超,关勇,齐明,李朝晖,王江..高频重复经颅磁刺激对精神分裂症患者阴性症状改善作用持续性的随访研究[J].中国当代医药,2018,25(16):12-15,4.基金项目
北京市大兴区科技发展计划项目(KT2016000053) （KT2016000053）
