中国当代医药2018，Vol.25Issue(16)：36-40,5.
线粒体形态与功能改变在肿瘤中的研究进展
Research Progress of Mitochondrial Morphological and function changes in Tumor
摘要
Abstract
Mitochondria are the regulatory center for cellular energy metabolism,substance synthesis,and death.In the development and progression of tumor,mitochondria as an important regulator,have a significant impact on the biological behaviors including tumor proliferation,migration,differentiation,and invasion.To approach the changes of mitochondrial morphology and function,as well as their regulatory mechanism in the development and progression of tumor,will undoubtedly be the key to using mitochondria as a new generation of cancer therapeutic target.In this paper,the advances in the role of mitochondria in tumor development and progression are reviewed,in an attempt to elucidate the close association between them.关键词
线粒体/代谢重编程/氧自由基/线粒体DNA/肿瘤Key words
Mitochondria/Metabolic reprogramming/ROS/Mitochondrial DNA/Tumor分类
医药卫生引用本文复制引用
郑弘毅,吴雄健,杨建芬,张克,刘瑶..线粒体形态与功能改变在肿瘤中的研究进展[J].中国当代医药,2018,25(16):36-40,5.基金项目
国家自然科学基金资助项目(81660406) （81660406）
赣南医学院研究生创新专项资金项目(YC2016-X008) （YC2016-X008）
