临床输血与检验2018，Vol.20Issue(1)：68-72,5.DOI:10.3969/j.issn.1671-2587.2018.01.024
2012～2016金黄色葡萄球菌和肺炎链球菌分布及耐药趋势分析
Analysis of Staphylococcus Aureus and Streptococcus Pneumoniae Distribution and Drug Resistance Trend of 2012-2016
摘要
Abstract
Objective To investigate the current status of Staphylococcus aureus and streptococcus pneumoniae infection in our hospital from 2012 to 2016 and their drug resistance in order to provide reference for clinical medication. Methods The retrospective analysis was performed on the separation condition and the drug resistance of Staphylococcus aureus and streptococcus pneumoniae from the bacterial culture among the inpatients of our hospital from 2012 to 2016. Results A total of 18 966 strains of pathogenic bacteria were isolated from all kinds of specimens, and 1 697 strains of Staphylococcus aureus were isolated. Among them, 623 strains were methicillin resistant Staphylococcus aureus (MRSA), accounting for 36.71％, Streptococcus pneumoniae 353, and the isolation rate was 1.86％.The main sources of the samples were sputum, secretion and blood; the departments with Staphylococcus aureus infection were mainly the ICU, neurosurgery, orthopedics and geriatric ward.The isolation rate of SA in 5 years and the antimicrobial resistance rate showed a continuous slow downward trend, but the detection rate of MRSA had no obvious change.The results of SP showed that no vancomycin or linezolid resistant strains were found, The resistance rates of erythromycin, clindamycin, tetracycline and sulfamethoxazole were higher, There was a certain fluctuation of drug sensitivity in 2012-2016 year.Conclusion Our hospital SA hospital infection control is better, but the drug resistance of SP isolated from our hospital was not optimistic, clinicians should still pay more attention to the clinical rational use of antibiotics according to drug susceptibility test results.关键词
金黄色葡萄球菌/肺炎链球菌/耐药性/趋势Key words
Staphylococcus aureus/Streptococcus pneumoniae/Drug resistance/Trend分类
医药卫生引用本文复制引用
金亮,李达,王勇雁,陈丹丹,刘辉,郝殿晋,陈宏伟..2012～2016金黄色葡萄球菌和肺炎链球菌分布及耐药趋势分析[J].临床输血与检验,2018,20(1):68-72,5.基金项目
本课题受秦皇岛市科技支撑计划项目(No.201502AD78)资助 （No.201502AD78）
