临床输血与检验2018，Vol.20Issue(1)：79-82,4.DOI:10.3969/j.issn.1671-2587.2018.01.027
NLR、PLR、RDW在感染性休克诊断、监测及预后评估中的应用
Clinical Application of NLR, PLR and RDW to Diagnosis, Monitoring and Prognosis of Septic Shock
摘要
Abstract
Objective To study clinical significance of NLR, PLR and RDW in the diagnosis, dynamic monitoring and prognosis of septic shock. Methods One hundred and fifty-five cases of septic shock (group death: 76 deaths, cured group:79 cases) and 155 cases of healthy control were subjected to NLR, PLR and RDW blood testing. A comparison was made in PCT, WBC, RDW, PLR and NLR for their efficiency in diagnosis of septic shock. Results PCT, WBC, RDW, PLR and NLR tests in cases group revealed a statistical significance. The diagnostic sensitivity and specificity were 96.1％ and 95.5％, respectively when 4.68 was taken as NLR diagnosis threshold, and 72.3％ and 66.4％, respectively when 14.62 was used as PLR threshold. PCT had significantly positive correlation with NLR and PLR (r=0.884, 0.599). The mortality of septic shock was 49.03％. A difference was seen between PCT and RDW in deaths and cured individuals. Patient outcome had positive correlation with PCT and RDW (r=-0.165, -0.449).Conclusion NLR and PLR had positive correlation with PCT, that can be used to for diagnosis and dynamic monitoring in septic shock patients due to their convenience, economy, and easy application.关键词
感染性休克/降钙素原/中性粒细胞/淋巴细胞比值/血小板/淋巴细胞比值/红细胞分布宽度Key words
Septic shock/Procalcitonin/Neutroplhil to lymphocyte ratio/Platelet to lymphocyte ratio Red blood cell distribution width分类
医药卫生引用本文复制引用
陈伟,刘艳,刘金菊,戴小辉,肖小红,肖扬..NLR、PLR、RDW在感染性休克诊断、监测及预后评估中的应用[J].临床输血与检验,2018,20(1):79-82,4.基金项目
本课题受中央引导地方科技发展专项(No.2017CT5028)、娄底市科技创新计划项目(NO.LDKJ201706)资助 （No.2017CT5028）
