外科理论与实践2018，Vol.23Issue(2)：125-129,5.DOI:10.16139/j.1007-9610.2018.02.009
原发性甲状旁腺功能亢进症临床分析(附138例报告)
Clinical analysis of primary hyperparathyroidism: a report of 138 cases
李富新 1姜若愚 1李东洋 1陈作宇 1魏铭泽 1张柏 1何向辉1
作者信息
- 1. 天津医科大学总医院普通外科,天津 300052
- 折叠
摘要
Abstract
Objective To summarize the experience in the diagnosis and treatment of primary hyperparathyroidism (PHPT). Methods The clinical data of 138 patients with PHPT who underwent parathyroidectomy in our hospital from January 2015 to November 2017 were analyzed retrospectively. Results The patients including 30 males and 108 females were all treated with surgical treatment. Five cases had parathyroid crisis and 1 case underwent emergent surgery. A total of 150 parathyroid glands were resected. Postoperative pathology confirmed that 123 (82. 0％) lesions were parathyroid adenoma, 9 (6. 0％) lesions parathyroid hyperplasia, 4 (2. 7％) lesions parathyroid carcinoma, 10 (6. 6％) lesions parathyroid cysts and 4 (2. 7％) lesions parathyroid atypical adenoma. Parathyroid hormone decreased to normal and the blood calcium decreased in all cases after parathyroidectomy. The symptoms of hypocalcemia were found in 48 cases whose blood calcium restored to normal after supplementation of active vitamin D and calcium gluconate. There were no recurrent laryngeal nerve injury and other complications. Conclusions Blood calcium and parathyroid hormone can be used in the diagnosis of PHPT in early stage. Parathyroidectomy is an effective treatment for PHPT. Preoperation precise localization is helpful for the exploration of pathological lesion. Management with hydration diuresis and bisphosphonates and early parathyroidectomy have good effect on parathyroid crisis.关键词
原发性甲状旁腺功能亢进症/甲状旁腺危象/甲状旁腺切除术Key words
Primary hyperparathyroidism/Parathyroid crisis/Parathyroidectomy分类
医药卫生引用本文复制引用
李富新,姜若愚,李东洋,陈作宇,魏铭泽,张柏,何向辉..原发性甲状旁腺功能亢进症临床分析(附138例报告)[J].外科理论与实践,2018,23(2):125-129,5.
