外科理论与实践2018，Vol.23Issue(2)：140-144,5.DOI:10.16139/j.1007-9610.2018.02.012
肝脏局灶性结节增生的诊治
Diagnosis and treatment of patients with focal nodular hyperplasia
摘要
Abstract
Objective To review the experience of diagnosis and treatment of focal nodular hyperplasia (FNH) in our department for the management of FNH represents a challenge. Methods Twenty-two cases with FNH from October 2010 to January 2017 were studied retrospectively. All patients were diagnosed as FNH by postoperative pathological assessment. Results Twelve male cases and 10 female cases with FNH were recruited with sex ratio 1. 2∶1. 0 and mean age (32. 50±8. 38)(18-50) years. Three cases manifested clinical symptoms with 3 cases of abdominal pain and one case of high CA-724 level. The others had no any symptoms. Seventeen cases were diagnosed as FNH by imaging. All cases received surgical therapy with operating time (142. 72±54. 81) (50-300) min, operative blood loss (397. 27±466. 95) (50-1 700) mL and hospital stay(7. 90±2. 86) (4-15) days, There was no both severe morbidity and mortality peri-operatively and no recurrent case was found during the period of follow-up from 11 to 75 months. Conclusions FNH is a rare benign proliferative lesion of liver with rare clinical symptoms and characterized by central scar. Combination of several imaging modalities would be valuable to the diagnosis. For the patients with symptomatic FNH, combined with hepatitis and cirrhosis or difficult to distinguished from hepatic cancer or hepatic adenoma, surgical resection should be considered and the prognosis is better.关键词
肝肿瘤/局灶性结节增生/诊断/治疗Key words
Hepatic tumors/Focal nodular hyperplasia (FNH)/Diagnosis/Therapy分类
医药卫生引用本文复制引用
管若愚,马迪,杨奎,龚笑勇,陈拥军..肝脏局灶性结节增生的诊治[J].外科理论与实践,2018,23(2):140-144,5.基金项目
国家自然科学基金(61672341) （61672341）
