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性传播途径在广州地区无偿献血者HCV感染及传播中的风险研究

陈锦艳 黄杰庭 黄珂 戎霞 付涌水 王敏 蓝琴 陈小萍 黎世杰 许茹 廖峭 王淏 单振刚

中国输血杂志2018,Vol.31Issue(2):120-123,4.
中国输血杂志2018,Vol.31Issue(2):120-123,4.DOI:10.13303/j.cjbt.issn.1004-549x.2018.02.007

性传播途径在广州地区无偿献血者HCV感染及传播中的风险研究

The risk of sexual transmission in HCV infection and transmission in Guangzhou voluntary blood donors

陈锦艳 1黄杰庭 1黄珂 1戎霞 1付涌水 1王敏 1蓝琴 1陈小萍 1黎世杰 1许茹 1廖峭 1王淏 1单振刚1

作者信息

  • 1. 广州血液中心广州市医学重点实验室,广东 广州 510080
  • 折叠

摘要

Abstract

Objective To investigate the risk of sexual transmission in HCV infection and transmission in Guangzhou blood donors. Methods 153 HCV-RNA positive blood donors donating during October, 2009-July, 2013 were contacted to attend the study with their sexual partners. In the study, their anti-HCV and HCV-RNA were tested. The questionnaires were issued to understand their lifestyles. If their sexual partners were also HCV-RNA positive, their HCV-RNA will be further genotyped. The Kimura Genetic Distance is calculated to determine whether the infection is from their sexual partners. Statistical risk factor analysis was performed based on age groups to evaluate the HCV infection in these blood donors. Results 48 pairs of blood donors and their sexual partners were successfully followed-up. 48 HCV-RNA positive blood donors were classified as HCV-1b (27), 2a (2), 3a (5), 3b (2) and 6a(12) . There was no statistically significant difference in the age distribution of potential risk factors for these donors (P>0. 05) . Their sexual partners were all anti-HCV ELISA and HCV-RNA negative. Conclusion The risk of sexual transmission of HCV infection in blood donors in the Guangzhou region is likely to be very low.

关键词

HCV/性传播/无偿献血者/广州/风险研究

Key words

HCV/sexually transmitted route/volunteer blood donors/Guangzhou/risk study

分类

医药卫生

引用本文复制引用

陈锦艳,黄杰庭,黄珂,戎霞,付涌水,王敏,蓝琴,陈小萍,黎世杰,许茹,廖峭,王淏,单振刚..性传播途径在广州地区无偿献血者HCV感染及传播中的风险研究[J].中国输血杂志,2018,31(2):120-123,4.

基金项目

广东省科技计划项目(2016A020216001) ,广东省自然基金重点项目(: 2014A030311005) ,广东省医学科学技术研究基金项目(2016071 (2016A020216001)

2016310) ()

中国输血杂志

OACSTPCD

1004-549X

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