中国体外循环杂志2018，Vol.16Issue(1)：7-11,5.DOI:10.13498/j.cnki.chin.j.ecc.2018.01.03
体外膜肺氧合在新生儿复杂先天性心脏病术后救治中的效果分析
Effect of extracorporeal membrane oxygenation in neonates with complex congenital heart disease after cardiac surgery
摘要
Abstract
Objective To summarise the clinical application of extracorporeal membrane oxygenation (ECMO) in the treatment of heart failure or cardiac arrest after neonatal cardiac surgery to provide a basis for further improvement of the success rate of ECMO. Methods Clinical data of 10 neonates who received ECMO support after cardiac surgery in our center from September 2016 to October 2017 were retrospectively analyzed. Results Ten neonates, aged from 2 to 25 days and weighed between 2.60 to 4.50 kg, with heart failure or cardiac arrest after open heart surgery were supported with ECMO. The duration for ECMO was from 11 to 456 hours. Six (60％) neonates were successfully weaned from ECMO and four (40％) survived to discharge. Among them, Six deaths happened in hospital, including three cases giving up treatment and three cases died of unsuccessful weaning from ECMO due to cardiac dysfunction. Bleeding, acute kidney injury and infection were the most common complications. Heart failure and abandoned treatment were two major causes of death. Conclusions ECMO could provide effective support for neonates with cardiac failure or cardiac arrest after surgery for congenital heart disease. Mastering timing and indications, improving the management of ECMO, emphasizing on the protection of organ function and reducing the incidence of complications are important factors to improve the survival rate.关键词
新生儿/体外膜肺氧合/先天性心脏病/心功能衰竭/心脏骤停Key words
Extracorporeal membrane oxygenation/Congenital heart disease/Cardiac failure/Cardiac arrest引用本文复制引用
于新迪,张海波,杨寅愉,沈佳,张明杰,刘玉洁,张蔚,王伟,朱德明,徐卓明..体外膜肺氧合在新生儿复杂先天性心脏病术后救治中的效果分析[J].中国体外循环杂志,2018,16(1):7-11,5.基金项目
上海市卫生计生委联合攻关项目(3013ZYJB0013) （3013ZYJB0013）
国家自然科学基金项目(81670372) （81670372）
