针灸临床杂志2018，Vol.34Issue(1)：47-50,4.
针刀松解术对类风湿关节炎肘关节僵硬患者血清氧自由基代谢水平的影响
Effect of Acupotomy on the Metabolism of Serum Oxygen Free Radicals in Rheumatoid Arthritis Patients with Elbow Stiffness
摘要
Abstract
Objective:To observe the serum changes of MDA and SOD in rheumatoid arthritis (RA) patients with elbow joint stiffness by acupotomy, and to explore the mechanism of acupotomy. Methods:60 RA patients were divided into the basic treatment group, the acupuncture group, and the acupotome group, with 20 cases in each group. All patients were treated with the basic treatment of traditional Chinese and western medicine. The basic treatment group was not given local treatment of the elbow joint. The acupuncture group and the acupotomy group were also treated with acupuncture and acupotomy correspondingly. At the end of the treatment, the elbow venous blood was collected and the changes of serum MDA, SOD, ESR, CRP and RF were detected. Results:After the treatment, MDA level of each group showed a downward trend and SOD level showed an upward trend, the difference was significant compared to those before the treatment (P ＜0. 05); the changes of the acupotomy group was more significant compared to those of the basic treatment group and the acupuncture group (P ＜0. 05). In terms of the levels of ESR, CRP and RF, they were significantly decreased in the acupuncture group and the acupotome group after the treatment (P ＜0. 05); of which there were significant differences in the acupuncture group and the acupotome group, compared to the basic treatment group(P ＜0. 05); the decreasing level was more significant in the acupotome group than that in the acupuncture group(P ＜0. 05). Conclusion: Acupotomy treatment can increase SOD content, effectively remove excess free radicals, thus to relieve stiffness of RA.关键词
针刀疗法/类风湿关节炎/肘关节僵硬/MDA/SODKey words
Acupotomy/Rheumatoid arthritis/Stiffness of elbow joint/MDA/SOD分类
医药卫生引用本文复制引用
万碧江,黄伟,任婕,陈丽川..针刀松解术对类风湿关节炎肘关节僵硬患者血清氧自由基代谢水平的影响[J].针灸临床杂志,2018,34(1):47-50,4.基金项目
武汉市临床医学科研项目,编号:WZ14C01 （）
