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己糖激酶对肿瘤作用的研究进展

邓晓霖 厉周

中国现代医生2018,Vol.56Issue(13):164-168,5.
中国现代医生2018,Vol.56Issue(13):164-168,5.

己糖激酶对肿瘤作用的研究进展

Research progress of the effects of hexokinase on tumor

邓晓霖 1厉周1

作者信息

  • 1. 南方医科大学珠江医院普通外科,广东广州 510282
  • 折叠

摘要

Abstract

Objective The characteristic metabolic way of tumor cells is aerobic glycolysis, the Warburg effect. Hexokinase is the key enzyme of glycolysis and highly and widely expressed in tumor cells. It is considered to be related with metabolism, apoptosis and autophagy of tumor. By conducting researches on hexokinase and its upstream and downstream, it would be possible to find out the potential gene targeting therapy which could be effective to several kinds of tumors.

关键词

己糖激酶/Warburg效应/糖酵解/凋亡/自噬肿瘤

Key words

Hexokinase/Warburg Effect/Glycolysis/Apoptosis/Autophagy/Tumor

分类

医药卫生

引用本文复制引用

邓晓霖,厉周..己糖激酶对肿瘤作用的研究进展[J].中国现代医生,2018,56(13):164-168,5.

中国现代医生

1673-9701

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