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磷酸铝凝胶预防儿童静脉滴注阿奇霉素胃肠道反应的效果观察

陈洁如 过毅

儿科药学杂志2018,Vol.24Issue(6):20-21,2.
儿科药学杂志2018,Vol.24Issue(6):20-21,2.DOI:10.13407/j.cnki.jpp.1672-108X.2018.06.007

磷酸铝凝胶预防儿童静脉滴注阿奇霉素胃肠道反应的效果观察

Aluminum Phosphate Gel in Preventing Gastrointestinal Reactions Caused by Intravenous Azithromycin in Children

陈洁如 1过毅1

作者信息

  • 1. 江苏省无锡市第二人民医院,江苏 无锡 214002
  • 折叠

摘要

Abstract

Objective: To investigate the clinical efficacy of aluminum phosphate gel in preventing gastrointestinal reactions caused by intravenous azithromycin in children. Methods: One hundred and forty-six children with Mycoplasma pneumoniae pneumonia accepting intravenous azithromycin therapy from Jan. to Dec. 2016 were randomly divided into treatment group (n =83)and control group (n =63). The treatment group was orally administrated with aluminum phosphate gel 30 minutes before intravenous azithromycin therapy, while the control group did not treated with aluminum phosphate gel. Gastrointestinal reactions of two groups were observed. Results: The incidence of gastrointestinal reactions of treatment group was 30. 1%, yet the control group was 81. 0%, the difference was statistically significant(χ2 =37. 08, P<0. 01). Conclusion: Aluminum phosphate gel can prevent gastrointestinal reactions caused by intravenous azithromycin in children.

关键词

磷酸铝凝胶/阿奇霉素/胃肠道反应

Key words

aluminum phosphate gel/azithromycin/gastrointestinal reactions

分类

医药卫生

引用本文复制引用

陈洁如,过毅..磷酸铝凝胶预防儿童静脉滴注阿奇霉素胃肠道反应的效果观察[J].儿科药学杂志,2018,24(6):20-21,2.

儿科药学杂志

OACSTPCD

1672-108X

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