摘要
Abstract
Objective To investigate the effect of hemoperfusion combined with hemodialysis on serum inflammatory factors and renal function in patients with chronic renal failure.Methods 106 cases of patients with chronic renal failure in our hospital from January 2015 to May 2017 were chosen as experimental subjects,and were divided into control group and research group.The control group was treated with hemodialysis on the basis of routine treatment,the research group was treated with hemoperfusion on the basis of the control group.After 12 weeks of treatment,the expression levels ofhs-CRP,IL-1,IL-6,TNF-α,PTH,P,β2-MG,Hcy,Scr,BUN were compared between the two groups.Results After treatment,the levels of inflammatory factors in the two groups significantly decreased,and the levels of IL-1,IL-6,hs-CRP,and TNF-α in the research group were lower than those in the control group,with statistically significant differences (P＜0.05).After treatment,the levels of renal function indexes in the two groups significantly decreased,and the levels of β2-MG,BUN,and Scr in the research group were lower than those in the control group,with statistically significant differences (P＜0.05).After treatment,the levels of clinical indexes in the two groups significantly decreased,and the levels of Hcy,PTH,and P in the research group were lower than those in the control group,with statistically significant differences (P＜0.05).Conclusion Hemoperfusion combined with hemodialysis can effectively improve renal function and inflammatory response in patients with chronic renal failure.关键词
慢性肾衰竭/血液透析/血液灌流/肾功能/炎症反应Key words
Chronic renal failure/Hemodialysis/Hemoperfusion/Renal function/Inflammatory reaction
