世界中医药2018，Vol.13Issue(8)：1925-1928,1932,5.DOI:10.3969/j.issn.1673-7202.2018.08.026
苏子降气汤治疗痰浊壅肺型慢性阻塞性肺疾病稳定期的疗效观察
Curative Effect Observation of Suzi Jiangqi Decoction in the Treatment of Chronic Obstructive Pulmonary Disease with Phlegm-turbidity Accumulation Syndrome at Stable Stage
摘要
Abstract
Objective:To observe the clinical curative effect of Suzi Jiangqi Decoction in the treatment of chronic obstructive pul -monary disease with phlegm-turbidity accumulation syndrome , and to evaluate the effects on pulmonary function improvement. Methods:A total of 60 cases of phlegm-turbidity accumulation in patients with chronic obstructive pulmonary disease in our hospi -tal from January 2016 to December 2017 as the research object ,were randomly divided into the western medicine group ( WM group) (30 cases) and the combination of traditional Chinese and western medicine group (TCM and WM group) (30 cases) by the digital random method.The western medicine group took the simple western medicine treatment ,and the combination of TCM and WM group had western medicine treatment +Suzi Jiangqi Decoction,continuous treatment for 30 d.The differences between the two groups with clinical curative effect ,symptom integrals and arterial blood gas analysis (oxygen partial pressure concentration PaO2),pulmonary function and fractional exhaled nitric oxide (FeNO) before and after the treatment were compared.Results:The clinical total effective rate of the WM group and the combination of TCM and WM group were respectively 86.67%and 66.67%. The statistical analysis showed that the combination of TCM and WM group was superior to the WM group .The clinical symptoms integrals,6 min walking distance,concentration of oxygen partial pressure ,pulmonary function levels of both groups were improved. The combination of TCM and WM group improved more significantly ,and the differences were statistically significant (P＜0.05). FeNO decreased in both groups after the treatment.The combination of TCM and WM group decreased more significantly ,and the differences were statistically significant (P＜0.05).Conclusion:Suzi Jiangqi Decoction was with significant clinical curative effect in phlegm-turbidity accumulation syndrome of chronic obstructive pulmonary disease ,can improve pulmonary ventilation in the pa-tients.The mechanism may be related to the reduction of FeNO concentration.关键词
慢性阻塞性肺疾病/痰浊壅肺型/稳定期/苏子降气汤/肺功能/FeNOKey words
Chronic obstructive pulmonary disease/Phlegm-turbidity accumulation in the lung syndrome/Stable period/Suzi Jiangqi Decoction/Pulmonary function/FeNO分类
医药卫生引用本文复制引用
李扭扭,史利卿,马建岭,季坤,温绍惠,王丽云..苏子降气汤治疗痰浊壅肺型慢性阻塞性肺疾病稳定期的疗效观察[J].世界中医药,2018,13(8):1925-1928,1932,5.基金项目
北京市中医管理局青年基金项目(QN21013-23) （QN21013-23）
