世界中医药2018,Vol.13Issue(8):2055-2058,4.DOI:10.3969/j.issn.1673-7202.2018.08.056
多毛症与非多毛症多囊卵巢综合征妇女基线特征与临床结局
Baseline Characteristics and Clinical Outcomes in Women with Hirsutism and Non-hirsutism Polycystic Ovary Syndrome
摘要
Abstract
Objective:To investigate the differences in baseline characteristics and treatment outcomes between hirsutism and non -hirsutism polycystic ovary syndrome patients ,and to provide a theoretical basis for the syndrome characteristics and diagnosis and treatment of polycystic ovary syndrome.Methods:This study was a secondary analysis based on a multicenter ,randomized,double-blind,placebo-controlled infertility clinical trial.According to the Rotterdam diagnostic criteria ,644 women with infertility polycys-tic ovary syndrome were included in 19 sub-centers between November 2009 and February 2013.Subjects were divided into hirsut-ism group (HI group,≥5 points) and non-hirsutism group (Non-HI group,<5 points) according to the Ferriman-Gallwey scoring criteria.The differences in baseline characteristics and clinical outcomes between the two groups were compared .Results:1.Base-line characteristics:waist circumference,diastolic blood pressure,heart rate,LH and LH/FSH levels were significantly lower in the HI group than in the Non-HI group (P<0.05),while the proportion of the acne score and the bilateral ovary "necropic sign" was higher than Non-HI group (P<0.05); 2.Clinical outcomes:The pregnancy rate of subjects in HI group was significantly lower than that in Non-HI group (P=0.04).Conclusion:The hirsutism and non-hirsutism polycystic ovary syndrome subjects have dif-ferent clinical phenotypic characteristics.The hirsutism polycystic ovary syndrome subjects have the characteristics of low concep-tion rate.关键词
多囊卵巢综合征/多毛症/基线特征/临床结局Key words
Polycystic ovary syndrome/Hirsutism/Baseline characteristics/Clinical outcome分类
医药卫生引用本文复制引用
高敬书,何慧,王宇,吴效科..多毛症与非多毛症多囊卵巢综合征妇女基线特征与临床结局[J].世界中医药,2018,13(8):2055-2058,4.基金项目
黑龙江中医药大学科研基金项目-面上项目(黑龙江省教育厅联合项目)(201727) (黑龙江省教育厅联合项目)
黑龙江省教育厅2017年度黑龙江省普通本科高等学校青年创新人才计划(UNPYSCT-2017226) (UNPYSCT-2017226)