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氯胺酮对川金丝猴的麻醉效应

杨万吉 张波 夏茂华 姚辉 刘金鹏 余辉亮 徐海清 杨敬元 向左甫

兽类学报2018,Vol.38Issue(3):295-301,7.
兽类学报2018,Vol.38Issue(3):295-301,7.DOI:10.16829/j.slxb.150186

氯胺酮对川金丝猴的麻醉效应

The anesthetic effects of ketamine on golden snub-nosed monkeys (Rhinopithecus roxellana)

杨万吉 1张波 2夏茂华 1姚辉 3刘金鹏 4余辉亮 3徐海清 4杨敬元 4向左甫4

作者信息

  • 1. 中南林业科技大学生命科学与技术学院,长沙 410004
  • 2. 湖北神农架金丝猴保育生物学湖北省重点实验室,湖北神农架 442421
  • 3. 北京动物园,圈养野生动物技术北京市重点实验室,北京 100044
  • 4. 湖北神农架金丝猴保育生物学湖北省重点实验室,湖北 神农架 442421
  • 折叠

摘要

Abstract

To evaluate the anesthetic effect of ketamine on golden snub-nosed monkeys (Rhinopithecus roxellana),we observed the reaction of 24 individuals to intramuscular injection of ketamine doses of 5. 90-15. 71 mg/kg when collecting blood for another study. The results indicated that all individuals had a satisfactory anesthetic outcome with no deaths. They exhibited limpness,salivation,slow falling,and occasional idle chewing during incubation which lasted (4. 00 ± 1. 77) min. They showed good muscle relaxation,smooth breathing,and idle chewing during the anesthesia period which lasted (21. 67 ± 5. 03) min. The recovery period lasted (31. 79 ± 6. 07) min; golden snub-nosed monkeys began to regain consciousness,tried to sit and walk with frequent idle chewing during the recovery period,and resumed normal activities after the recovery period. A new behavior,idle chewing,i. e. chewing with no food in the mouth,is first reported in the process of anesthesia in this species. Furthermore,our results show that the duration of the recovery period was longer for the male subjects than for the females and that the frequency of idle chewing during the recovery period was lower in the males than in the females. Sex and age dependent differences in behavioral reactions were not detected during the anesthesia or in the recovery period.

关键词

氯胺酮/川金丝猴/麻醉

Key words

Anesthesia/Golden snub-nosed monkeys/Ketamine

分类

生物科学

引用本文复制引用

杨万吉,张波,夏茂华,姚辉,刘金鹏,余辉亮,徐海清,杨敬元,向左甫..氯胺酮对川金丝猴的麻醉效应[J].兽类学报,2018,38(3):295-301,7.

基金项目

国家科技支撑计划(2013BAD03B00) (2013BAD03B00)

兽类学报

OA北大核心CSCDCSTPCD

1000-1050

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