外科理论与实践2018，Vol.23Issue(4)：342-345,4.DOI:10.16139/j.1007-9610.2018.04.014
术中出血对早期肝细胞癌病人围术期及预后的影响
Intraoperative hemorrhage related to perioperative events and prognosis of patients with early stage hepatocellular carcinoma
摘要
Abstract
Objective To explore intraoperative bleeding of patients with early stage hepatocellular carcinoma which may relate to perioperative events and the prognosis.Methods A retrospective analysis was performed on 222 patients with early stage hepatocellular carcinoma who underwent surgical resection in Tianjin Medical University Cancer Hospital from January 2008 to December 2013.According to the receiver operating characteristic curve analysis of the volume of intra-operative blood loss, 185 cases with blood loss 200 m L or less were assigned into group A and 37 cases with blood loss more than 200 m L into group B.Hospital stay, complication and overall survival were compared between two groups.Results There were no significant difference in gender, age, preoperative platelet counting, prothrombin time and total serum bilirubin and diameter and number of tumor between two groups statistically (P>0.05).Longer median survival time of the patients, shorter hospital stay, less cases with ascites and infection were found in group A when compared those in group B (P<0.05).Conclusions For patients with early stage hepatocellular carcinoma, intraoperative bleeding may be a negative factor for the perioperative complications and long term survival.It is necessary to reduce the bleed-ing during hepatectomy.关键词
肝细胞癌/肝切除术/术中出血/并发症/预后Key words
Hepatocellular carcinoma/Hepatectomy/Intraoperative hemorrhage/Complications/Prognosis分类
医药卫生引用本文复制引用
张勇强,张倜,孔银龙,侯振宇,李慧锴,崔云龙,宋天强,李强..术中出血对早期肝细胞癌病人围术期及预后的影响[J].外科理论与实践,2018,23(4):342-345,4.基金项目
国家自然科学基金 (81672884) （81672884）
国家科技重大专项-艾滋病和病毒性肝炎等重大传染病防治 (2017ZX10203207-004-005) （2017ZX10203207-004-005）
天津市科技重大专项与工程-精准医疗重大专项 (15ZXJZSY00030) （15ZXJZSY00030）
