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保胆取石术后结石复发的相关影响因素分析

刘强 陈士水 邵慧成 孟庆东 吕晔源 赵君

中国普通外科杂志2018,Vol.27Issue(8):983-988,6.
中国普通外科杂志2018,Vol.27Issue(8):983-988,6.DOI:10.3978/j.issn.1005-6947.2018.08.006

保胆取石术后结石复发的相关影响因素分析

Analysis of factors associated with postoperative stone recurrence after gallbladder-preserving cholecystolithotomy

刘强 1陈士水 1邵慧成 1孟庆东 1吕晔源 1赵君1

作者信息

  • 1. 山东省医学科学院第三附属医院 肝胆外科/山东省寄生虫病防治研究所,山东 济宁 272033
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摘要

Abstract

Objective: To investigate the related factors for stone recurrence in patients with gallbladder stones after gallbladder-preserving cholecystolithotomy. Methods: The clinical and follow-up data of 400 patients with gallbladder stones undergoing gallbladder-preserving cholecystolithotomy from May 2010 to May 2014 were collected. The factors for postoperative stone recurrence of the patients were analyzed. Results: In the 400 patients, the average follow-up time was (34.2±3.6) months, and gallbladder stone recurrence occurred in 42 cases (10.5%). The results of univariate analysis showed that having a family history of gallstones, degree of gallbladder wall thickness, number of stones and triacylglycerol level were significantly associated with postoperative stone recurrence (all P<0.05); multivariate Logistic regression analysis revealed that having a family history of gallstones (OR=10.231, 95% CI= 6.344-48.343, P=0.008); gallbladder wall thickness >4 mm (OR=2312, 95% CI=1.223-12.156,P=0.023), multiple gallstones (OR=4.568, 95% CI=3.213-15.328,P=0.015) and triacylglycerol level >1.71 mmol/L (OR=2.556, 95% CI=1.643-15.312, P=0.041) were independent risk factors for postoperative stone recurrence. Conclusion: Having a family history of gallstones; gallbladder wall thickness >4 mm; multiple gallstones and triglyceride level >1.71 mmol/L are risk factors for postoperative stone recurrence in gallstone patients after gallbladder-preserving stone extraction. For patients with these factors, the appropriate preventive measures should be considered or gallbladder-preserving procedure should not be performed.

关键词

胆囊结石病/器官保留治疗/复发/危险因素

Key words

Cholecystolithiasis/Organ Sparing Treatments/Recurrence/Risk Factors

分类

医药卫生

引用本文复制引用

刘强,陈士水,邵慧成,孟庆东,吕晔源,赵君..保胆取石术后结石复发的相关影响因素分析[J].中国普通外科杂志,2018,27(8):983-988,6.

中国普通外科杂志

OA北大核心CSCDCSTPCD

1005-6947

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