中国医学工程2018，Vol.26Issue(6)：38-42,5.DOI:10.19338/j.issn.1672-2019.2018.06.011
植入术后心电图预测心脏再同步化治疗疗效的研究
Postimplantation electrocardiogram prediction of clinical response to cardiac resynchronization therapy
张亮琳 1谢桂玉 1谭碧涛 1曹龙勇 1熊胜兰1
作者信息
- 1. 湘南学院附属医院 心电图室,湖南 郴州 423000
- 折叠
摘要
Abstract
[Objective]To investigate whether the presence or absence of RV1SI predicts heart failure outcomes within 1 year of cardiac resynchronization therapy (CRT) implant.[Methods]Two independent physicians reviewed the paced electrocardiogram (ECG) of 213 patients with post-CRT device implantation; when disputes occurred, it was resolved by a third reviewer. The primary end points of all-cause death, unplanned hospitalization, left ventricular assist device implant, or transplant within a 1-year follow-up were blindly adjudicated according to standard definitions. Groups were compared via Kaplan-Meier estimates and Cox proportional hazards models were used to determine the association with event-free survival.[Results]Among CRT patients postimplantation, 56 (26.3％) exhibited the RV1SI pattern on ECG. Patients with the RV1SI pattern were significantly less likely to achieve the primary end point as compared to patients without the RV1SI pattern (41.07％ vs 61.79％; Log Rank P =0.022). This difference was driven by a significantly lower risk for unplanned hospitalization among patients with the RV1SI pattern [hazard ratio =0.510; confidence interval (0.298, 0.876) ]. The predictive value remained after adjustment for potential confounders (P =0.004).[Conclusions]The 12-lead ECG postimplantation predicts clinical outcomes of biventricular (Bi V) pacing. Such prediction may be useful in predicting the need for alternative or advanced heart failure therapies. Further study into ECG patterns may help to prospectively guide CRT.关键词
双心室起搏/心脏再同步治疗/心电图/充血性心力衰竭Key words
biventricular pacing/cardiac resynchronization therapy/electrocardiogram/congestive heart failure分类
医药卫生引用本文复制引用
张亮琳,谢桂玉,谭碧涛,曹龙勇,熊胜兰..植入术后心电图预测心脏再同步化治疗疗效的研究[J].中国医学工程,2018,26(6):38-42,5.
