中国输血杂志2018，Vol.31Issue(6)：670-672,3.DOI:10.13303/j.cjbt.issn.1004-549x.2018.06.029
两种冷沉淀凝血因子制备方法的比较研究
Quality evaluation of two preparation strategies of cryoprecipitate
姜燕娟 1师玉红 1聂军 1任红霞1
作者信息
- 1. 新乡市中心血站,河南 新乡 453000
- 折叠
摘要
Abstract
Objective To analyze the FⅧ content and fibrinogen content in cryoprecipitate products prepared by different instruments and protocols. Methods Fresh frozen plasma (FFP) prepared from 400 m L whole blood was randomly divided into 2 groups. The first group was prepared by CYTOTHERM-4 T. 6 C low temperature melting tank; The second group was prepared by ZBK-LCD-A1 type cold precipitation preparation instrument. Blood coagulation analyzer was used for F Ⅷand fibrinogen content detection, which served the bases for statistical analysis. Results Product analysis results by the two instruments: Factor Ⅷ (FⅧ ∶ C): (94. 2 ± 18. 1) vs (113. 0 ± 32. 9) IU; Fibrinogen (Fgb) content: (218. 1 ± 39. 3) vs (230. 9±34. 1) mg; Factor Ⅷ content qualification rates: 79. 2％ vs 100％; Fibrinogen content qualification rates 97. 9％ vs93. 8％. FⅧ concent results presented statistically significant differences while fibrinogen content results showed otherwise.Conclusion Both preparation strategies met national standards. The preparation quality of ZBK-LCD-A1 type is better and the efficiency is higher.关键词
冷沉淀凝血因子/Ⅷ因子含量/纤维蛋白原含量Key words
cryoprecipitate/factor Ⅷ content/fibrinogen分类
医药卫生引用本文复制引用
姜燕娟,师玉红,聂军,任红霞..两种冷沉淀凝血因子制备方法的比较研究[J].中国输血杂志,2018,31(6):670-672,3.
