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超分子水杨酸外用治疗轻、中度痤疮疗效观察

唐莉 尹锐 罗娜 肖艳 刘悦玲 夏爱爱 李朝惠 杨利

中国美容医学2018,Vol.27Issue(9):31-33,3.
中国美容医学2018,Vol.27Issue(9):31-33,3.

超分子水杨酸外用治疗轻、中度痤疮疗效观察

Clinical Investigation of Supramolecular Salicylic Acid in the Treatment of Mild to Middle Acne Vulgaris

唐莉 1尹锐 1罗娜 1肖艳 1刘悦玲 1夏爱爱 1李朝惠 1杨利1

作者信息

  • 1. 陆军军医大学第一附属医院皮肤科 重庆 400038
  • 折叠

摘要

Abstract

Objective To investigate the clinical efficacy and safety of supramolecular salicylic acid to treat mild to moderate acne vulgaris. Methods 140 cases of mild to moderate facial acne vulgaris patients were randomly divided into two groups: 70 cases in the experimental group treated by supramolecular salicylic acid and 70 cases in the control group (0.1% adapalene gel). Both of two groups accepted the treatment for 12 weeks.Two independent investigators evaluated outcomes and recorded side-effects at 1 and 3 months post-treatment. Results The effective rate of the experimental group was 50.72% and 91.3% respectively at 1 and 3 months post-treatment. Meanwhile, the control group was 28.36% and 46.27% respectively. There was significant difference between the two groups (P<0. 05). The incidence of adverse reactions of the treatment group was 5.8%, the control group was 59.70%. There were no obvious side-effects in both groups. Conclusion The combination treatment of acne vulgaris with glycolic acid is benefit for moderate to severe acne vulgaris. The side-effects is less and worth to apply in clinics.

关键词

超分子化学/水杨酸/痤疮/化学换肤术

Key words

supramolecular chemistry/salicylic acid/acne/chemical peeling

分类

医药卫生

引用本文复制引用

唐莉,尹锐,罗娜,肖艳,刘悦玲,夏爱爱,李朝惠,杨利..超分子水杨酸外用治疗轻、中度痤疮疗效观察[J].中国美容医学,2018,27(9):31-33,3.

中国美容医学

OACSTPCD

1008-6455

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