吉林中医药2018，Vol.38Issue(10)：1161-1163,3.DOI:10.13463/j.cnki.jlzyy.2018.10.014
芪参益气滴丸治疗慢性心力衰竭疗效评价
Evaluation of curative effect for Qishen Yiqi gutta pills in the treatment of chronic heart failur
摘要
Abstract
Objective To investigate the clinical efficacy of Qishen Yiqi gutta pills in the treatment of chronic heart failure (CHF). Methods CHF patients (n = 186), 46 to 79 (average 68.3±13.6) years old, were chosen from outpatient and inpatient in our hospital from Jan. 2016 to Dec. 2017, and then randomly divided into Qishen Yiqi Gutta Pills treatment group (n = 95) and control group (n = 91). The selected patients were treated for standard heart failure. The treatment group added Qishen Yiqi gutta pills (0.5 g) once 0.5 g and 3 times a day for 12 weeks. The changes of left ventricular diastolic diameter, left ventricular ejection fraction (EF), plasma NT-proBNP and 6 min walking test were compared between two groups before and after treatment. Results The total effective rate was 88.4 % in treatment group. the plasma NT-proBNP level decreased significantly, the left ventricular diastolic diameter decreased, the LVEF increased, and the 6 min walking distance increased, all of which were significantly better than the control group. The difference was statistically significant (P＜0.01 or P＜0.05). Conclusion The efficacy of Qishen Yiqi gutta pills is significant in CHF patients, which can improve heart function, activity endurance and quality of life.关键词
芪参益气滴丸/慢性心力衰竭/疗效评价Key words
Qishen Yiqi gutta pills/chronic heart failure/evaluation of curative effect分类
医药卫生引用本文复制引用
郑立文,刘晨,段英春,姜丽艳,林琳,李博睿..芪参益气滴丸治疗慢性心力衰竭疗效评价[J].吉林中医药,2018,38(10):1161-1163,3.基金项目
吉林省自然科学基金项目"320排CT冠脉成像评价冠状动脉不稳定斑块与危险因素关系的研究"(20130101176JC). （20130101176JC）
