继续医学教育2018，Vol.32Issue(10)：140-143,4.DOI:10.3969/j.issn.1004-6763.2018.10.076
肺炎克雷伯菌在天津市环湖医院的感染现状、分布特点及耐药性分析
The Infection Status, Distribution and Antibiotic Resistance of Klebsiella Pneumoniae in Tianjin Huanhu Hospital
摘要
Abstract
] Objective To investigate the clinical distribution and antibiotic resistance of Klebsiella pneumoniae isolated from Tianjin Huanhu Hospital from January to December 2017, to provide evidence for clinical rational drug use and infection control. Methods The isolation of bacteria is according to national clinical laboratory operation procedures. The distribution and antibiotic resistance of 600 isolates of K. pneumoniae were retrospectively analyzed. Results From January to December 2017, 600 non-repetitive K. pneumoniae strains were isolated, followed by 307 strains of Acinetobacter baumannii, 229 strains of Escherichia coli, 224 strains of Serratia marcescens, 212 strains of Pseudomonas aeruginosa, and K. pneumoniae ranked first. The detection rate of K. pneumoniae in ICU was the highest (19%), followed by craniocerebral emergency ward 2 (10%) and neurosurgical ward 7 (8%). K. pneumonia-positive specimens were mostly derived from sputum (92%), cerebrospinal fluid (3%) and urine (3%). ESBLs-producing K. Pneumoniae was detected in 36.7% of the 220 isolates. The resistance of K. pneumoniae to most drugs in ICU is higher than the average level. Conclusion Klebsiella pneumoniae accounted for the largest proportion of clinical isolates, showing different degrees of resistance to antibiotics.关键词
肺炎克雷伯菌/耐药性/超广谱β-内酰胺酶(ESBLs)Key words
Klebsiella pneumoniae/Extend-spectrumβ-lactamase (ESBLs)/antibiotic resistance分类
医药卫生引用本文复制引用
张乐,胡静怡,杨萍,于海淼,颜艳..肺炎克雷伯菌在天津市环湖医院的感染现状、分布特点及耐药性分析[J].继续医学教育,2018,32(10):140-143,4.基金项目
天津市自然科学基金(No.16JCQNJC10200) （No.16JCQNJC10200）
天津市卫生局科学基金(No.2014KY8) （No.2014KY8）
