陕西中医2018，Vol.39Issue(11)：1602-1605,4.DOI:10.3969/j.issn.1000-7369.2018.11.033
抗喘利肺汤联合西药治疗小儿哮喘临床研究
Clinical effect of Kangchuan Lifei decoction with western medicine in Children bronchial asthma with positive allergens action
摘要
Abstract
Objective :To explore the clinical effect of Kangchuan Lifei decoction with western medicine in bronchial asthma children with positive allergens action .Methods :278 bronchial asthma children with positive aller-gens action in our hospital were divided control group and observe group by a random way ,139 cases in each group . The control group was treated by routine western medical treatment ,while Kangchuan Lifei decoction was treated in observe group on the base of control group .After the treatment ,the effects in the 2 groups were compared .Before and after the treatment ,the levels of lung function [average expiratory flow peak (PEF) ,lung capacity (FVC) ,1s force expiratory volume (FEV1/FVC%) and one second forced expiratory volume (FEV1)] were detected ,while traditional Chinese medicine syndrome scores (chest tightness ,cough ,expectoration ,shortness breath and inhala-tion) were observed in the two groups .Before and after the treatment ,the levels of asthma markers [toll-like recep-tor 2 (TLR2) ,eosinophil chemotactic factor (Eotaxin) ,eosinophilic cationic protein (ECP) ,macrophage inflamma-tory protein-1 alpha (MIP-1α) and serum amyloid A (SAA)] were detected in the 2 groups .Results :After the treatment ,the effect rate in the observe group was significantly higher than control group (P＜0 .05).After the treatment ,the levels of PEF ,FVC ,FEV1/FVC% and FEV1 were significantly higher in the observe group ,while the levels of TLR2 ,Eotaxin ,ECP ,MIP-1α and SAA were significantly promoted than the control group (P＜0 . 05).After the treatment ,the scores of chest tightness ,cough ,expectoration ,shortness breath and inhalation in the observe group were significantly lower than the observe group (P＜0 .05).Conclusions :Kangchuan Lifei decoction with western medicine in bronchial asthma children with positive allergens action has a good effect .关键词
哮喘/中西医结合疗法/儿童/@抗喘利肺汤Key words
Asthma/integrated Chinese traditional and western medicine therapy/Child/@Kangchuan Lifei decoction分类
医药卫生引用本文复制引用
樊英,康淑红..抗喘利肺汤联合西药治疗小儿哮喘临床研究[J].陕西中医,2018,39(11):1602-1605,4.基金项目
陕西省教育厅自然科学研究项目(2013JK0773) （2013JK0773）
